Micro-CT scan of rabbit tibia blood vessels

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             Micro-CT scan of rabbit tibia blood vessels
Experimental purpose: The blood vessels near the tibia of the rabbit (the blood vessel has been injected with contrast agent) were detected by Micro-CT instrument to observe the morphology and distribution of blood vessels near the tibia.
Experimental method: The experiment was carried out by the small animal Micro-CT scanning equipment of Guangzhou Zhongke Yusheng Company. The experimental sample is placed in a Micro-CT instrument for scanning, and after the scanning is completed, the obtained raw data data is reconstructed and analyzed in three dimensions and the image is taken.
Experimental results: The image quality obtained by Micro-CT is much better in fineness than human CT. It can see many tiny blood vessels that humans can't see with CT, such as capillaries with a diameter of only a few tens of microns.
Below, I will briefly introduce the experimental content and results.
Experimental content :
The blood vessel was internally injected with a BaSO 4 contrast agent, and the specimen was fixed with a formalin solution. When scanning, the sample is fixed by the mold and placed in the instrument. The scanning parameters of the Micro-CT instrument are set as follows: voltage 60Kvp, power 40W, 4 frames superimposed, and field of view 4 cm×4 cm for scanning. After the scan, the original data is obtained for overall reconstruction, and then the local reconstruction is performed according to the region of interest to obtain two-dimensional and three-dimensional images of the blood vessel.
Experimental results:
Picture 1-1 is a two-dimensional slice obtained after partial reconstruction after scanning. From this picture we can clearly see the microscopic state of the blood vessel and its number.
The next figure 1-2 is the reconstructed three-dimensional image. From the picture we observe that a large number of blood vessels are intertwined around the bone, which provides the most intuitive data for the distribution of blood vessels near the bone.
Figure 1-3 is a three-dimensional view of the blood vessels. We separate the bones and blood vessels by adjusting the threshold, leaving only the blood vessels of the sample, which gives us a clearer and more intuitive understanding of the morphological structure, size and distribution of the blood vessels. And knowing.
From the above data, it is not difficult to see that Micro-CT has a very high resolution compared to ordinary clinical CT, can reach the micrometer (μm) level, has a good "microscopic" effect, and it can also not destroy the sample. Understand the internal microstructure of the sample. This is of great help to the preservation of the sample and the subsequent experiments.
Micro-CT has a wide range of applications, including bones, teeth, angiography, and polymer materials. Micro-CT has an unshakable position in the study of fine bone morphology, bone density, and trabecular parameters. At present, many valuable high-end bone research papers at home and abroad are obtained through the Micro-CT platform. Academic papers based on the Micro-CT of Zhongke Yusheng have been published in the world's top medical journals and journals. If you have research needs in this area, you can log on to our company's homepage http:// to learn about the latest developments in our products and services.

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