Ketoconazole is a synthetic antifungal drug used to prevent and treat fungal skin infections, especially in immunocompromised patients such as those with AIDS or those on chemotherapy. Ketoconazole is sold commercially as an anti-dandruff shampoo, topical cream, and oral tablet. Minoxidil is a potassium channel agonist. It contains the chemical structure of nitric oxide), a blood vessel dilator, and may be a nitric oxide agonist. This appears to explain its vasodilatory effects, but may also be linked to minoxidil's ability to stimulate hair growth and treat hair loss. Since minoxidil is a nitric oxide-related compound, it was suspected to act via activation of guanylate cyclase, an enzyme involved in vasodilation. Ketoconazole is a synthetic antifungal drug used to prevent and treat fungal skin infections, especially in immunocompromised patients such as those with AIDS or those on chemotherapy. Ketoconazole is sold commercially as an anti-dandruff shampoo, topical cream, and oral tablet. Minoxidil is a potassium channel agonist. It contains the chemical structure of nitric oxide), a blood vessel dilator, and may be a nitric oxide agonist. This appears to explain its vasodilatory effects, but may also be linked to minoxidil's ability to stimulate hair growth and treat hair loss. Since minoxidil is a nitric oxide-related compound, it was suspected to act via activation of guanylate cyclase, an enzyme involved in vasodilation.
Quick Details:
Product name : Ketoconazole
CAS No.:65277-42-1
Other Names:Ketoconazole
MF:C26H28Cl2N4O4
EINECS No.:265-667-4
Place of Origin: ShenZhen, China (Mainland)
Type:Antifungal
Grade Standard:Medicine Grade, Tech Grade
Usage: For the treatment of systemic fungal infections
Brand Name: SENDI
Model Number:Top Grade
Purity:99.9%min
Application:Fine Chemical Intermediate
Grade:Medicine Grade
Storage temp.:2-8°C
MP:146°C
Stock:avaiable
Shelf life:2 Years
COA:avaiable
Assay:HPLC 99%
Appearance:White or off-white crystal Powder
Usage: used for the treatment of superficial and deep fungal disease
Ketoconazole introduction:
Application:Â
Hair loss
Ketoconazole shampoo in conjunction with an oral 5α-reductase inhibitor has been used off label to treatÂ
and rogenic alopecia.Â
The antifungal properties of ketoconazole reduce scalp microflora and consequently may reduce follicular inflammation that contributes to alopecia.Limited clinical studies suggest ketoconazole shampoo used either alone or in combination with other treatments may be useful in reducing hair loss. At least one study has been performed showing that ketoconazole may be useful in temporarily reducing erectile function in postoperative penile surgery patients.
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Veterinary use
Ketoconazole is also sometimes prescribed by veterinarians for use on pets, often as unflavored tablets that may need to be cut to smaller size for correct dosage.
Functions of Ketoconazole:Â
Ketoconazole is usually prescribed for fungal infections of the skin and mucous membranes, such as athlete's foot, ringworm, candidiasis (yeast infection or thrush), jock itch, and tinea versicolor.
Topical ketoconazole is also used as a treatment for dandruff (seborrheic dermatitis of the scalp) and for seborrheic dermatitis on other areas of the body, perhaps acting in these conditions by suppressing levels of the fungus Malassezia furfur on the skin.
Treat systemic fungal infections, Such as systemic candidiasis, coccidioidomycosis deputy, histoplasmosis,coccidioidomycosis, blastomycosis
treat Gastrointestinal yeast infections
For hand ringworm, tinea pedis, tinea, jock itch and cutaneous candidiasis and tinea versicolor
Dosage
Apply the cream to the affected 2-3 times daily after washing.
Specification
Items
StandardÂ
Results
Characters
white or almost white powder
Qualified
Identification
Meets the requirements
Qualified
Melting range
148°C ~ 152°C
148.0~ 150.0°C
Appearance of solution
Meets the requirements
Qualified
Organic volatile impurities
Meets USP30
Qualified
Specific rotation
-1° ~ +1°(USP30)
0°
Â
-0.10° ~ +0.10°(EP5.0,BP2005)
Â
Chromatographic purity
Meets the requirements
Qualified
Heavy metals
≤0.002%
Qualified
Loss on drying
≤0.5%
0.001
Residue on ignition
≤0.1%
0.0005
Assay
98.0% ~ 102.0%(USP30)
0.9969
Â
99.0%~101.0%(EP5.0,BP2005)
Â
CONCLUSION:
This is certify that the product complies to the standards of USP29,EP5.0,BP2005
Packing&Storage
Â
Â
Packaging Detail
0.5kgs/Al-Bottle
1.0kgs/Al- Bottle
2.0kgs/Al- Bottle
5.0 kgs/Al-Bottle
25.0 kgs/drum
or upon customers' request.
Quick Details:
Product name : Ketoconazole
CAS No.:65277-42-1
Other Names:Ketoconazole
MF:C26H28Cl2N4O4
EINECS No.:265-667-4
Place of Origin: ShenZhen, China (Mainland)
Type:Antifungal
Grade Standard:Medicine Grade, Tech Grade
Usage: For the treatment of systemic fungal infections
Brand Name: SENDI
Model Number:Top Grade
Purity:99.9%min
Application:Fine Chemical Intermediate
Grade:Medicine Grade
Storage temp.:2-8°C
MP:146°C
Stock:avaiable
Shelf life:2 Years
COA:avaiable
Assay:HPLC 99%
Appearance:White or off-white crystal Powder
Usage: used for the treatment of superficial and deep fungal disease
Ketoconazole introduction:
Application:Â
Hair loss
Ketoconazole shampoo in conjunction with an oral 5α-reductase inhibitor has been used off label to treatÂ
and rogenic alopecia.Â
The antifungal properties of ketoconazole reduce scalp microflora and consequently may reduce follicular inflammation that contributes to alopecia.Limited clinical studies suggest ketoconazole shampoo used either alone or in combination with other treatments may be useful in reducing hair loss. At least one study has been performed showing that ketoconazole may be useful in temporarily reducing erectile function in postoperative penile surgery patients.
Â
Veterinary use
Ketoconazole is also sometimes prescribed by veterinarians for use on pets, often as unflavored tablets that may need to be cut to smaller size for correct dosage.
Functions of Ketoconazole:Â
Ketoconazole is usually prescribed for fungal infections of the skin and mucous membranes, such as athlete's foot, ringworm, candidiasis (yeast infection or thrush), jock itch, and tinea versicolor.
Topical ketoconazole is also used as a treatment for dandruff (seborrheic dermatitis of the scalp) and for seborrheic dermatitis on other areas of the body, perhaps acting in these conditions by suppressing levels of the fungus Malassezia furfur on the skin.
Treat systemic fungal infections, Such as systemic candidiasis, coccidioidomycosis deputy, histoplasmosis,coccidioidomycosis, blastomycosis
treat Gastrointestinal yeast infections
For hand ringworm, tinea pedis, tinea, jock itch and cutaneous candidiasis and tinea versicolor
Dosage
Apply the cream to the affected 2-3 times daily after washing.
Specification
Items
StandardÂ
Results
Characters
white or almost white powder
Qualified
Identification
Meets the requirements
Qualified
Melting range
148°C ~ 152°C
148.0~ 150.0°C
Appearance of solution
Meets the requirements
Qualified
Organic volatile impurities
Meets USP30
Qualified
Specific rotation
-1° ~ +1°(USP30)
0°
Â
-0.10° ~ +0.10°(EP5.0,BP2005)
Â
Chromatographic purity
Meets the requirements
Qualified
Heavy metals
≤0.002%
Qualified
Loss on drying
≤0.5%
0.001
Residue on ignition
≤0.1%
0.0005
Assay
98.0% ~ 102.0%(USP30)
0.9969
Â
99.0%~101.0%(EP5.0,BP2005)
Â
CONCLUSION:
This is certify that the product complies to the standards of USP29,EP5.0,BP2005
Packing&Storage
Â
Â
Packaging Detail
0.5kgs/Al-Bottle
1.0kgs/Al- Bottle
2.0kgs/Al- Bottle
5.0 kgs/Al-Bottle
25.0 kgs/drum
or upon customers' request.
Ketoconazole CAS 65277-42-1 Strong 99% Antifungal Powder Diminish Inflammation
Model NO.: 65277-42-1
Mf: C30h44o3
MW: 452.67
Usage: Pharmaceutical Raw Materials
Package: 1kg/Bag
Specific Rotation: 120.0~123.0ºC
Melting Point: 120.0~123.0ºC
Payment Method: Tt, Wu, Mg, Wechat
Loss on Drying: 0.26%.
Organic Volatile Impurities: Meets The Requirements
Trademark: JZY
Transport Package: Disgusied Package
Specification: 99% USP
Origin: China
HS Code: 3001200010
Model NO.: 65277-42-1
Mf: C30h44o3
MW: 452.67
Usage: Pharmaceutical Raw Materials
Package: 1kg/Bag
Specific Rotation: 120.0~123.0ºC
Melting Point: 120.0~123.0ºC
Payment Method: Tt, Wu, Mg, Wechat
Loss on Drying: 0.26%.
Organic Volatile Impurities: Meets The Requirements
Trademark: JZY
Transport Package: Disgusied Package
Specification: 99% USP
Origin: China
HS Code: 3001200010